The SYMPLICITY trial is a type of research study called a clinical trial. A clinical trial is designed to test the safety or effectiveness of a new drug or device in humans. This clinical trial tests a new medical device meant for people whose high blood pressure cannot be controlled by different medications. The device has not yet been approved for the general public. The SYMPLICITY trial will include more than 500 people in more than 90 hospitals nationwide. To participate, people must be between 18 and 80 and on at least three doses of antihypertensive medication, one of which must be a diuretic (medicine that helps the body get rid of water and salt through urine).
If you want to enroll in the SYMPLICITY trial, you will be screened for the medications that you are currently taking. If you meet the study’s requirements, you will be asked to come in for a visit. Study visits take place in Oakland. Participants will be involved in three screening visits within 30 days and several follow-up visits for up to three years. If you participate in this trial, you may receive more frequent clinic visits and more information about your blood pressure. It may also decrease the amount and numbers of medications that you take.
If you’d like more information about high blood pressure or the SYMPLICITY trial, please call Lisa at 412-802-8672.

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